Aquaculture is rapidly growing in economic importance in the USA, where California (CA) is considered as an emergent leader aquaculture industry worth an estimated $110 million per year. The primary aquaculture species in the state are salmonids, particularly Oncorhynchus sp. However, these fish are affected by many endemic infectious agents such hematopoietic necrosis virus (IHNV), cutthroat trout virus (CTV), bacterial kidney disease (BKD), Flavobacterium columnare and F. psychrophilum.